Engineering a dual-action nitric oxide and propolis releasing polymeric matrix for extended antimicrobial efficacy.

Aasma Sapkota, Sadah Schell, Mofoluwasade O Popoola, Hitesh Handa, Elizabeth J Brisbois

Abstract read

In one paragraph

Article in Journal of materials chemistry. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aasma SapkotaSchool of Chemical, Materials, & Biomedical Engineering, University of Georgia, Athens, 30602, USA. ejbrisbois@uga.edu.

Sadah SchellSchool of Chemical, Materials, & Biomedical Engineering, University of Georgia, Athens, 30602, USA. ejbrisbois@uga.edu.

Mofoluwasade O PopoolaSchool of Chemical, Materials, & Biomedical Engineering, University of Georgia, Athens, 30602, USA. ejbrisbois@uga.edu.

Hitesh HandaSchool of Chemical, Materials, & Biomedical Engineering, University of Georgia, Athens, 30602, USA. ejbrisbois@uga.edu.ORCID http://orcid.org/0000-0002-9369-7374

Elizabeth J BrisboisSchool of Chemical, Materials, & Biomedical Engineering, University of Georgia, Athens, 30602, USA. ejbrisbois@uga.edu.ORCID http://orcid.org/0000-0002-9283-5448

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection of indwelling medical devices is one of the major healthcare threats, often resulting in sepsis, device failure, and even death. The conventional treatment approach for these infections is often systemic, utilizing antibiotics that may lead to unwanted side effects or the development of antibiotic-resistant bacteria. This has led to research into an effective antimicrobial technique that would not further contribute to antimicrobial resistance. Nitric oxide (NO) releasing materials are excellent antimicrobial agents that effectively thwart multiple bacterial strains. Additionally, the incorporation of natural antimicrobial agents such as propolis is a facile and cost-effective way to increase the efficacy and longevity of NO releasing materials without posing any cytotoxic concern. Herein, the fabrication of a NO and propolis releasing polymeric matrix enhanced antimicrobial efficacy against

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsNitric OxidePolymersPropolisAnimalsCandida albicansCell SurvivalEscherichia coliMiceMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsNitric OxidePolymersPropolis

Identifiers

PMID42149043

DOI10.1039/d6tb00666c

PMCPMC13181844

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.