ArticleLab on a chip2026
3D printing monolithic, multifunctional polymer acoustofluidic devices with tunable mixing and particle focusing.
Article in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
Funding
Abstract
Acoustic forces offer a powerful, contact-free modality for manipulating particles and fluids within microfluidic lab-on-a-chip systems. However, realizing the full potential of acoustic manipulation has been constrained by conventional cleanroom-based fabrication methods. Typically formed from high-acoustic-impedance materials like silicon or glass, these processes yield devices with limited design complexity owing to the planar channel geometries inherent in micromachining. Here, we introduce a class of polymer-based acoustofluidic platforms fabricated using micro-digital light processing (μDLP) 3D printing. In contrast to micromachining, this additive manufacturing approach enables complex, truly three-dimensional (3D) microfluidic architectures in a monolithic device form factor. We demonstrate strategies to overcome challenges associated with low-acoustic-impedance polymer resins and establish design rules based on precise control over channel and surrounding material dimensions (
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