Evidence map›Paper›PMID 42148754›Full record

ArticlemBio2026

Competition between commensal protists shapes gut mucosal immunity in mice.

Marienela Y Heredia, Paul A Kuehnert, Kylie March, Laura J Knoll, Claire E O'Leary

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marienela Y HerediaDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0001-6247-1252
Paul A KuehnertDepartment of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
Kylie MarchDepartment of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
Laura J KnollDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-9362-8088
Claire E O'LearyDepartment of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0001-9052-4593

Funding

Food Research Institute Carol L. Deibel Distinguished Graduate Fellowship in Probiotic Research from the Food Research InstituteNIH HHS K22-AI166029NIH HHS R01-AI144016-01UW-Madison SciMed Graduate Research Scholars Fellowship
6 · The paper itself

Abstract

Intestinal protists are emerging as key modulators of host immunity and microbial ecology, yet their impact on mammalian hosts remains poorly defined. Here, we investigated the role of two distinct protists, the amoeba IMPORTANCE: Single-cell parasites called protists are common in mammalian intestinal tracts, yet their modulation of the host immune response and interactions with each other remain poorly defined. Here, we investigated the role of two protists,

Indexed as

EntamoebaImmunity, MucosalIntestinal MucosaSymbiosisTritrichomonasAnimalsColonFemaleIntestine, SmallMaleMiceMice, Inbred C57BLTuft CellsEntamoebaTritrichomonastuft celltype 2 immunity

Identifiers

PMID42148754
PMCPMC13251391

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.