Evidence map›Paper›PMID 42148579›Full record

ArticleMicrobiology spectrum2026

Multi-site microbiomes' response to chronic obstructive pulmonary disease.

Mingxuan Liu, Wei Zhang, Jing Zhang, Na Lv, Xiukun Wu, Adel I Alalawy, Wenfan Zhao, Hairong Bao, Jianjun Wu

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingxuan Liu *School of Public Health, Gansu University of Chinese Medicine, Lanzhou, China.
Wei Zhang *The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Jing ZhangSchool/Hospital of Stomatology, Lanzhou University, Lanzhou, China.
Na LvThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
Xiukun WuKey Laboratory of Extreme Environmental Microbial Resources and Engineering, Lanzhou, China.ORCID 0009-0006-5803-0028
Adel I AlalawyDepartment of Biochemistry, Faculty of Science, University of Tabuk, Tabuk, Kingdom of Saudi Arabia.
Wenfan ZhaoThe Second Hospital & Clinical Medicine School, Lanzhou University, Lanzhou, China.
Hairong BaoThe First School of Clinical Medicine, Lanzhou University, Lanzhou, China.ORCID 0000-0003-1791-2869
Jianjun WuSchool of Public Health, Gansu University of Chinese Medicine, Lanzhou, China.ORCID 0009-0000-6203-0588

Funding

Science and technology project in Gansu 24JRRA876Science and technology project in Gansu 25JRRA509The joint research major project foundation of Gansu 23YFFA0033
6 · The paper itself

Abstract

This study aimed to evaluate changes in the oral, nasal, pulmonary, and gut microbiota in patients with chronic obstructive pulmonary disease (COPD) and to explore their interrelationships compared with the healthy group. This study included 33 COPD patients and 29 healthy individuals. A total of 162 oral, nasal, sputum, and fecal samples were obtained. The microbiota was determined using full-length 16S rRNA gene sequencing on the PacBio platform. Alpha diversity was significantly reduced in sputum and fecal samples of COPD patients, while oral and nasal microbiota showed no significant differences. Beta diversity revealed substantial overlap between oral and sputum microbiota in both groups, while nasal and fecal communities were clearly distinct. Linear discriminant analysis effect size analysis identified

Indexed as

BacteriaMicrobiotaPulmonary Disease, Chronic ObstructiveAgedFecesFemaleGastrointestinal MicrobiomeHumansLungMaleMiddle AgedMouthNasal CavityRNA, Ribosomal, 16SSputumRNA, Ribosomal, 16Schronic obstructive pulmonary diseasefull-length 16S rRNA gene sequencingmicrobial dysbiosisoral-lung-gut axis

Identifiers

PMID42148579
PMCPMC13340062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.