Evidence map›Paper›PMID 42148340›Full record

ArticleCase reports in orthopedics2026

Sequential Limb Lengthening: A Novel Staged Approach Combining External Fixation and a Motorized Intramedullary Lengthening Nail for a Large Posttraumatic Tibial Defect.

T Cerasoli, G Balboni, C Musiani, M Zaffagnini, A Burla, G M Marcheggiani Muccioli, S Zaffagnini, M Romagnoli

Abstract read
In one paragraph

Article in Case reports in orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

T CerasoliDepartment of Biomedical and Neuromotor Sciences DIBINEM, Alma Mater Studiorum University of Bologna, Bologna, Italy, unibo.it.ORCID https://orcid.org/0000-0003-1111-5869
G BalboniDepartment of Biomedical and Neuromotor Sciences DIBINEM, Alma Mater Studiorum University of Bologna, Bologna, Italy, unibo.it.ORCID https://orcid.org/0009-0001-6815-5397
C MusianiOrtopedia e Traumatologia Rizzoli Argenta, Rizzoli Orthopaedic Institute, Argenta (FE), Italy, ior.it.
M ZaffagniniDepartment of Biomedical and Neuromotor Sciences DIBINEM, Alma Mater Studiorum University of Bologna, Bologna, Italy, unibo.it.ORCID https://orcid.org/0009-0006-2108-3740
A BurlaOrtopedia e Traumatologia Rizzoli Argenta, Rizzoli Orthopaedic Institute, Argenta (FE), Italy, ior.it.ORCID https://orcid.org/0009-0004-7042-501X
G M Marcheggiani MuccioliDepartment of Biomedical and Neuromotor Sciences DIBINEM, Alma Mater Studiorum University of Bologna, Bologna, Italy, unibo.it.ORCID https://orcid.org/0000-0002-1087-2932
S ZaffagniniDepartment of Biomedical and Neuromotor Sciences DIBINEM, Alma Mater Studiorum University of Bologna, Bologna, Italy, unibo.it.ORCID https://orcid.org/0000-0002-2941-1407
M RomagnoliOrtopedia e Traumatologia Rizzoli Argenta, Rizzoli Orthopaedic Institute, Argenta (FE), Italy, ior.it.ORCID https://orcid.org/0000-0003-4004-3833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Managing large posttraumatic tibial defects presents significant challenges. External fixation is effective for distraction osteogenesis but has drawbacks, including prolonged treatment time and complications. Intramedullary lengthening nails improve patient comfort but have limitations in large bone transport. While combined techniques have been explored, to our knowledge a fully sequential approach where an external fixator is first used for distraction and then replaced by a motorized intramedullary lengthening nail continuing the lengthening has not been clearly described in the literature. This study presents a novel staged technique and a review of existing literature on limb lengthening strategies. Methods: We report the case of a 29-year-old male with a 16-cm posttraumatic tibial defect, treated with 10 cm of bone transport using an external fixator, followed by 6 cm of additional lengthening with a motorized intramedullary nail. Additionally, a literature search was conducted in PubMed, Scopus, and Embase using keywords related to limb lengthening, external fixation, and intramedullary nailing. The technique and outcomes were compared with existing literature. Discussion: The review did not identify any studies on fully sequential limb lengthening. Most studies focus on pediatric cases or hybrid techniques where external fixation and intramedullary nailing are used simultaneously. Our sequential approach allowed for controlled distraction and successfully addressed a 16-cm bone defect. Conclusions: This case highlights a previously undescribed staged limb lengthening approach. Sequential conversion from external fixation to a motorized intramedullary lengthening nail may offer advantages in reducing EFI, protecting neurovascular structures, and enhancing mechanical stability. Further research is needed to evaluate long-term outcomes.

Indexed as

distraction osteogenesisexternal fixationlimb lengtheningmotorized intramedullary nailsequential bone lengtheningstaged limb reconstruction

Identifiers

PMID42148340
PMCPMC13178156

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.