Evidence map›Paper›PMID 42148303›Full record

ArticleFrontiers in cell and developmental biology2026

Adipocytes from lipedema adipose tissue show lipoma-associated nuclear atypia.

M Steiner, M Rinnerthaler, A Mueller, E Russe, A-Th Lipp, H Bauer

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Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

M SteinerDepartment of Biosciences and Medical Biology, Paris Lodron University of Salzburg, Salzburg, Austria.
M RinnerthalerDepartment of Biosciences and Medical Biology, Paris Lodron University of Salzburg, Salzburg, Austria.
A MuellerDepartment of Biosciences and Medical Biology, Paris Lodron University of Salzburg, Salzburg, Austria.
E RusseDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hospital of the Brothers of St. John of God, Paracelsus Medical University, Salzburg, Austria.
A-Th LippPANTEA Private Practice for Plastic & Aesthetic Surgery and Lipedema Surgery, Munich, Germany.
H BauerDepartment of Biosciences and Medical Biology, Paris Lodron University of Salzburg, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lipedema, a painful disease that almost exclusively affects women, leads to an excessive accumulation of subcutaneous adipose tissue, primarily in the extremities. Morphologically, it is characterized by hyperplasia and hypertrophy of adipocytes as well as by inflammation-associated cells and fibrosis. Limited knowledge exists regarding the background of adipocyte pathology. In the present study, we aimed to identify morphological alterations of lipedema adipocytes, which could cause functional implications in lipedema adipose tissue. Methods: Approximately 3,000 adipocytes from nine lipedema and five control adipose tissue samples, originating from non-obese donors, were analyzed. The ratio of atypical nuclei ( Results: Lipedema adipose tissue exhibits a significantly higher proportion of Conclusion: The significantly increased occurrence of lipoma-associated

Indexed as

adipocyte nuclear atypialipedemalipomalipomatosislochkerne

Identifiers

PMID42148303
PMCPMC13176165

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