Evidence map›Paper›PMID 42148048›Full record

ArticleBioinformatics advances2026

New algorithms for unsupervised cell clustering from scRNA-seq data.

Melissa Robles, Jorge Díaz-Riaño, Cristhian Forigua, Sebastian Ojeda, Laura Guio, Paula Siaucho, Jennifer Guzman-Porras, Danilo García-Orjuela, Andres Naranjo, Silvia Maradei and 2 more

Abstract read
In one paragraph

Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Artificial intelligence-driven advancements in agricultural biotechnology.Journal, genetic engineering & biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Melissa RoblesSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.
Jorge Díaz-RiañoSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0001-6507-3612
Cristhian ForiguaSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.
Sebastian OjedaSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.
Laura GuioHOMI, Fundación Hospital Pediátrico La Misericordia, Bogotá, Colombia.
Paula SiauchoBiotecnología y Genética SAS, Biotecgen, Bogotá, Colombia.
Jennifer Guzman-PorrasHOMI, Fundación Hospital Pediátrico La Misericordia, Bogotá, Colombia.
Danilo García-OrjuelaBiotecnología y Genética SAS, Biotecgen, Bogotá, Colombia.
Andres NaranjoHOMI, Fundación Hospital Pediátrico La Misericordia, Bogotá, Colombia.
Silvia MaradeiBiotecnología y Genética SAS, Biotecgen, Bogotá, Colombia.
Adolfo QuirozDepartment of Mathematics, Universidad de los Andes, Bogotá, Colombia.
Jorge DuitamaSystems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-9105-6266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of cell types is a basic step of pipelines for Single-Cell RNA sequencing (scRNA-seq) data analysis. However, unsupervised clustering of cells from scRNA-seq data has multiple challenges: high dimensionality, sparseness of the expression matrix, and technical noise that generates false zero entries. In this study, we introduce new algorithms for clustering scRNA-seq data. The first algorithm builds a

Identifiers

PMID42148048
PMCPMC13176612

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.