Evidence map›Paper›PMID 42148037›Full record

ArticleDEN open2027

Improved Efficiency and Lesion Detection in Small Bowel Capsule Endoscopy Using the Open-Source Artificial Intelligence Model SEE-AI.

Satoshi Miyazono, Junji Umeno, Tomohiro Nagasue, Takuto Saiki, Hisamitsu Kaku, Takehiro Torisu, Akihito Yokote, Keisuke Kawasaki, Yutaro Ihara, Yuichi Matsuno and 10 more

Abstract read
In one paragraph

Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Satoshi MiyazonoDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Junji UmenoDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Tomohiro NagasueDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takuto SaikiDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Hisamitsu KakuDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takehiro TorisuDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Akihito YokoteDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Keisuke KawasakiDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yutaro IharaDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yuichi MatsunoDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Noriyuki ImazuDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Tomohiko MoriyamaDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Ahmed Nashaat MohamedThe National Hepatology and Tropical Medicine Research Institute Cairo Egypt.
Katsuya HirakawaDivision of Gastroenterology Fukuoka Red Cross Hospital Fukuoka Japan.
Hajime YamagataDepartment of Gastroenterology Hamanomachi Hospital Fukuoka Japan.
Yasuharu OkamotoDepartment of Gastroenterology Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers Fukuoka Japan.
Koichi KuraharaDivision of Gastroenterology Matsuyama Red Cross Hospital Ehime Japan.
Shinichiro YadaDepartment of Gastroenterology Onga Nakama Medical Association, Onga Hospital Fukuoka Japan.
Akira HaradaDivision of Gastroenterology Yamaguchi Red Cross Hospital Yamaguchi Japan.
Tetsuro AgoDepartment of Medicine and Clinical Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Small bowel capsule endoscopy (CE) produces lengthy videos that are time-consuming to review and susceptible to missed lesions. We evaluated whether an open-source, pretrained artificial intelligence (AI) model (SEE-AI) could improve diagnostic performance and interpretation efficiency compared with conventional reading. Methods: We retrospectively analyzed 249 PillCam SB3 examinations performed between 2007 and 2022 at six hospitals, using a two-reader crossover design. SEE-AI (confidence threshold 0.1) generated annotated videos with bounding boxes for eight lesion categories. The primary endpoints were sensitivity for lesion detection on a per-lesion and per-patient basis. Secondary endpoints included specificity, predictive values, overall accuracy, and reading time. A prespecified subgroup analysis evaluated cases of suspected small-bowel bleeding (SSBB), focusing on Saurin P1+P2 hemorrhagic lesions. Results: Across 1550 adjudicated lesions, AI-assisted reading demonstrated higher sensitivity than conventional reading (per-lesion: 98.8% [1532/1550] vs. 86.4% [1339/1550]; per-patient: 99.1% [464/468] vs. 80.3% [376/468]; both Conclusions: In this multicenter evaluation, SEE-AI significantly improved lesion detection and reduced reading time for CE interpretation, including SSBB cases, while maintaining openness and reproducibility. AI-assisted reading may reduce clinicians' workload and support the adoption of SEE-AI as a practical tool - and a potential future standard of care - for small bowel CE. Trial Registration: N/A.

Indexed as

artificial intelligencecapsule endoscopygastrointestinal tractsmall intestinesuspected small‐bowel bleeding

Identifiers

PMID42148037
PMCPMC13177839

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.