Evidence map›Paper›PMID 42148027›Full record

SynthesisProceedings (Baylor University. Medical Center)2026

Intraosseous versus intravenous vascular access during out-of-hospital cardiac arrest: a systematic review and meta-analysis.

Mohamed Saad Rakab, AlMothana Manasrah, Mohamed Rifai, Mohab Mattar, Ahmed A Ibrahim, Ibraheem Altamimi, Bashar M Al Zoubi, Mutaz Abu-Laila, Mohamed Abuelazm, Ahmed K Ghanem

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Proceedings (Baylor University. Medical Center), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohamed Saad RakabFaculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID https://orcid.org/0000-0003-2735-7483
AlMothana ManasrahDepartment of Internal Medicine, UHS-Wilson Medical Center, Binghamton, New York, USA.
Mohamed RifaiFaculty of Medicine, Menofyia University, Shebin El Kom, Egypt.
Mohab MattarFaculty of Medicine, Mansoura University, Mansoura, Egypt.
Ahmed A IbrahimDepartment of Internal Medicine, UHS-Wilson Medical Center, Binghamton, New York, USA.
Ibraheem AltamimiCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.
Bashar M Al ZoubiFaculty of Medicine, Hashemite University, Zarqa, Jordan.
Mutaz Abu-LailaKing Hussein Cancer Center, Amman, Jordan.
Mohamed AbuelazmFaculty of Medicine, Tanta University, Tanta, Egypt.
Ahmed K GhanemDepartment of Internal Medicine, Loma Linda University Medical Center, Murrieta, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Out-of-hospital cardiac arrest (OHCA) is a significant global healthcare burden, with survival rates remaining alarmingly low despite resuscitation advancements. This study aimed to evaluate the effect of intraosseous (IO) versus intravenous (IV) access for resuscitation on outcomes in OHCA. Methods: This systematic review and meta-analysis pooled data from studies retrieved from PubMed, CENTRAL, Scopus, and Web of Science up to August 2024. Risk ratios (RR) with 95% confidence intervals (CI) were calculated for all outcomes. Results: Twenty-one studies with a total of 249,138 patients were included. Compared to IV access, IO access was significantly associated with lower survival to admission (RR: 0.80, 95% CI [0.70, 0.90], Conclusion: IO access was associated with worse survival and neurological outcomes compared to IV access in OHCA resuscitation. Further research is needed to optimize vascular access strategies in emergency care.

Indexed as

Cardiopulmonary ResuscitationInfusions, IntraosseousOut-of-Hospital Cardiac ArrestHumansCardiac arrestintraosseous accessintravenous accessout-of-hospital-cardiac-arrestvascular access

Identifiers

PMID42148027
PMCPMC13174855

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.