ArticleBalkan journal of medical genetics : BJMG2025
Impact of Cholecystectomy on Gastric Mucosal c-MYC and h-TERT Expression; A Potential Link to Gastric Cancer Development.
Article in Balkan journal of medical genetics : BJMG, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Gastric cancer is a multifactorial malignancy influenced by genetic and environmental factors. Cholecystectomy may lead to bile reflux, causing potential gastric mucosal injury. hTERT and c-MYC are key regulators in cellular proliferation and oncogenesis. Although epidemiological data generally indicate no strong association between cholecystectomy and gastric cancer, existing studies are limited and confounded by other risk factors. This study aimed to investigate the contribution of bile acid exposure post-cholecystectomy to gastric cancer development and to evaluate hTERT and c-MYC expressions. A total of 100 participants were enrolled at Manisa Celal Bayar University Hospital (September 2021-May 2023), categorized into gastric cancer (n=32), cholecystectomy (n=34), and control groups (n=34). Demographic data,
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