ArticleQuantitative imaging in medicine and surgery2026
Dual-phase dual-energy computed tomography (DECT) in assessing recurrence-associated histopathological features of parotid pleomorphic adenoma.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Parotid pleomorphic adenoma (PA) is the most common benign salivary gland tumor but carries a risk of postoperative recurrence. Predicting its recurrence-associated histopathological features (stroma-rich subtype and capsular invasion) preoperatively could inform surgical planning. This study aimed to evaluate the efficacy of quantitative parameters derived from preoperative dual-phase dual-energy computed tomography (DECT) in predicting these two critical features. Methods: In this retrospective study, 108 patients with pathologically confirmed PA who underwent preoperative dual-phase enhanced DECT were enrolled. Quantitative DECT parameters including normalized iodine concentration (NIC), normalized effective atomic number (nZ Results: Stroma-rich group (35%, 38/108) showed significantly lower early-phase DECT parameters (nZ Conclusions: Dual-phase DECT provides valuable quantitative parameters for preoperatively predicting the stroma-rich subtype and capsular invasion in PA. The early-phase ∆HU is a promising single-parameter predictor for stromal richness, while a combined clinical-DECT model effectively predicts capsular invasion. This approach provides a preoperative tool for assessing recurrence risk, aiding in personalized surgical planning.
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