ArticleQuantitative imaging in medicine and surgery2026
Multiparametric magnetic resonance imaging (MRI) integrating amide proton transfer-weighted (APTw) imaging, synthetic MRI, and multiplexed sensitivity encoding diffusion-weighted imaging (MUSE DWI) in the diagnosis and grading of prostate cancer.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Prostate cancer (PCa) is a malignant tumor that significantly threatens the quality of life of elderly men. This study evaluated the efficacy of multiparametric magnetic resonance imaging (MRI) combining synthetic magnetic resonance imaging (SyMRI), amide proton transfer-weighted (APTw) imaging, and multiplexed sensitivity encoding diffusion-weighted imaging (MUSE DWI) in the diagnosis and grading of PCa. Methods: A total of 195 patients with pathologically confirmed prostate lesions who underwent the SyMRI, APTw, and MUSE DWI were retrospectively analyzed. Quantitative parameters derived from SyMRI [T1, T2, proton density (PD)], APTw (APT Results: Totals of 96 malignant and 99 benign patients were included in this study. In the transitional zone (TZ) and peripheral zone (PZ) of the prostate, all quantitative parameters except PD value showed statistical differences for distinguishing benign and malignant prostate lesions (P<0.05). T1, T2, and ADC values were significantly lower, whereas APT Conclusions: Multiparametric MRI incorporating SyMRI, APTw imaging, and MUSE DWI may offer enhanced diagnostic performance in distinguishing benign from malignant prostate lesions and grading of PCa.
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