Evidence map›Paper›PMID 42147798›Full record

ReviewJournal of inflammation research2026

Endothelial-Epithelial Crosstalk Drives Alveolar-Capillary Barrier Dysfunction in ARDS.

Juan Shi, Menglu Qiu, Siqi Han, Xulong Liu

Abstract readReview
In one paragraph

Review in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan ShiDepartment of Pediatrics, Chengdu Fifth People's Hospital, Chengdu, Sichuan, 611130, People's Republic of China.ORCID 0009-0002-3859-9138
Menglu QiuDepartment of Pediatrics, Chengdu Fifth People's Hospital, Chengdu, Sichuan, 611130, People's Republic of China.
Siqi HanDepartment of Pediatrics, Chengdu Fifth People's Hospital, Chengdu, Sichuan, 611130, People's Republic of China.
Xulong LiuDepartment of Pediatrics, Chengdu Fifth People's Hospital, Chengdu, Sichuan, 611130, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alveolar-capillary barrier (ACB) is essential to maintain the function of gas exchange. Acute respiratory distress syndrome (ARDS), is a critical disease characterized by complex etiology and significant clinical heterogeneity. ARDS is pathologically defined by the impairment of ACB integrity, fundamentally driven by maladaptive between alveolar epithelium and pulmonary endothelium that disrupt their coordinated barrier functions. This article systematically reviews the damage mechanism in ARDS, aiming to provide novel theoretical basis and research direction for clinical therapy optimization strategies and prognosis evaluation of ARDS.

Indexed as

acute respiratory distress syndromealveolar-capillary barrieralveolar epithelial cellsdysfunctionmechanismpulmonary vascular endothelial cells

Identifiers

PMID42147798
PMCPMC13179771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.