ArticleCureus2026
Non-resolving Pulmonary Consolidation Mimicking Tuberculosis: A Diagnostic Pitfall Revealing Lung Adenocarcinoma.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary tuberculosis (TB) remains highly prevalent in endemic regions; however, current international and national guidelines emphasize microbiological confirmation prior to initiation of anti-tubercular therapy (ATT) whenever feasible. Empirical treatment without microbiological confirmation represents a deviation from recommended standards and may contribute to diagnostic delay. We report a 52-year-old male presenting with chronic cough with mucoid expectoration and progressive dyspnea without fever, hemoptysis, or weight loss. Despite negative sputum acid-fast bacilli (AFB) smear and cartridge-based nucleic acid amplification test (CBNAAT), the patient was empirically initiated on ATT based on clinicoradiological suspicion. Lack of clinical and radiological response prompted further evaluation. High-resolution computed tomography (HRCT) demonstrated persistent consolidation with perilymphatic nodules and interlobular septal thickening. Positron emission tomography-computed tomography (PET-CT) revealed metabolically active pulmonary lesions with mediastinal lymphadenopathy and a suspicious adrenal lesion. CT-guided biopsy confirmed moderately differentiated lung adenocarcinoma. Molecular analysis revealed a KRAS mutation with negative programmed death-ligand 1 (PD-L1) expression. This case underscores the importance of adherence to diagnostic guidelines, early reconsideration of diagnosis in non-resolving consolidation, and the critical role of timely tissue diagnosis in preventing delays in oncological management.
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Registered trials
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