ReviewCureus2026
Comparative Radiological and Surgical Approaches in the Early Detection and Treatment of Colorectal Cancer: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the biggest causes of cancer mortality is still colorectal cancer (CRC), and outcomes depend heavily on timely detection, accurate staging, and curative-intent intervention, having been among the top five causes of cancer-related death globally since 1990 and, as of 2023, the leading cause of cancer-related death in individuals under 50. Evidence comparing radiological and surgical strategies remains fragmented across screening, staging, and treatment pathways, limiting direct translation into unified clinical workflows. This review aimed to compare the diagnostic and clinical utility of major imaging modalities with outcomes of surgical approaches used in early-stage CRC. A systematic search of electronic databases was conducted using MeSH and free-text terms, restricted to English-language human studies published between 2015 and 2025. Randomised trials and observational comparative studies were included, with data extracted on imaging accuracy, staging concordance, perioperative outcomes, recurrence, and survival, followed by narrative synthesis due to heterogeneity. Key outcomes showed CT colonography as a feasible screening alternative with cost-effectiveness dependent on participation, pelvic MRI as central for rectal staging and restaging, and PET-based techniques contributing mainly to surveillance and metastatic assessment. Surgical evidence supported minimally invasive colectomy and organ-preserving rectal pathways in selected patients, while emphasising morbidity risks and recurrence trade-offs. These findings support multidisciplinary integration of imaging-guided stratification with tailored surgical planning and biomarker-informed escalation or de-escalation. Limitations included variable protocols and inconsistent endpoint reporting. Precision imaging combined with appropriate surgery remains the most actionable strategy for improving early CRC outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.