Evidence map›Paper›PMID 42147642›Full record

ArticleCureus2026

Lattice Radiation Therapy as a Novel Approach for Renal Cell Carcinoma: A Case Series.

Spoorthi Vallamkonda, Jennifer S Chiang, Mark K Buyyounouski, Michael S Binkley, Hilary P Bagshaw

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Spoorthi VallamkondaDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.
Jennifer S ChiangDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.
Mark K BuyyounouskiDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.
Michael S BinkleyDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.
Hilary P BagshawDepartment of Radiation Oncology, Stanford University School of Medicine, Stanford, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatially fractionated radiation therapy (SFRT) is a treatment modality initially designed for large, deep-seated tumors. Lattice radiation therapy (LRT), a form of SFRT, delivers high and low doses of radiation (RT) in "peaks" and "valleys," utilizing a three-dimensional pattern while protecting the surrounding organs at risk. We present a case series of two patients with large renal tumors, which were treated with LRT as follows: a 30-year-old male with metastatic renal cell carcinoma (RCC) and a 72-year-old male with RCC and several other comorbidities who completed LRT with minimal toxicity. Both patients received 6670 cGy in 5 fractions delivered twice weekly. These cases support the potential role of LRT in tumor control and symptom palliation. Further research is warranted to delineate the long-term efficacy and toxicity profile of LRT.

Indexed as

kidney cancerlattice radiation therapyrenal cell carcinomaspatially fractionated radiation therapytumor control

Identifiers

PMID42147642
PMCPMC13179818

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.