Evidence map›Paper›PMID 42147631›Full record

ReviewCureus2026

Decision-Making in Pediatric Hematopoietic Stem Cell Transplantation: Perspectives of Physicians, Patients, and Families.

Luisa Arenas-Pérez, Andres F Calderon A, Diana Estrada

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luisa Arenas-PérezPediatrics, Pontificia Universidad Javeriana, Bogotá, COL.
Andres F Calderon APediatrics, Pontificia Universidad Javeriana, Bogota, COL.
Diana EstradaPediatrics, Pontificia Universidad Javeriana, Bogotá, COL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric hematopoietic stem cell transplantation (HSCT) is a complex therapeutic procedure that presents significant ethical, clinical, and psychosocial challenges. Decision-making in this context involves multiple stakeholders, including physicians, patients, and families, and is influenced by several medical and non-medical factors. This narrative review provides a descriptive synthesis of the literature to analyze the factors influencing decision-making in pediatric HSCT and to explore the roles and perspectives of the different actors involved in this process. Relevant literature was identified through searches of electronic databases, including PubMed, Scopus, Embase, and Web of Science, including studies published up to March 2024. Gray literature was not systematically included. The findings highlight that clinical condition, availability and understanding of information, socioeconomic context, religious beliefs, and perception of risks and benefits significantly influence treatment decisions. In addition, the perspectives of patients, parents, and healthcare professionals play a critical role in shaping the decision-making process. Shared decision-making, clear communication, and adequate psychological support are essential elements to facilitate informed and ethically sound decisions. Understanding these dynamics is fundamental to improving patient-centered care in pediatric transplantation.

Indexed as

decision-makingfamily perspectiveshematopoietic stem cell transplantationmedical ethicspediatric patientsshared decision-making

Identifiers

PMID42147631
PMCPMC13179779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.