ArticleCureus2026
Ocular Ultrasound Elastography for Intraocular Tumors: A Pilot Study.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ocular ultrasound elastography (OcUsE) was evaluated as a novel adjunct imaging modality for the characterization of intraocular tumors. In this prospective pilot study, 12 patients (12 eyes) with clinically and imaging-confirmed intraocular tumors underwent conventional B-scan ultrasonography complemented by strain and shear-wave elastography using a high-frequency linear probe. Quantitative tumor stiffness values, expressed in kilopascals, and qualitative elastographic patterns were recorded, correlated with multimodal imaging findings, and analyzed for diagnostic accuracy in differentiating benign from malignant lesions. Elastography was successfully performed in all cases without procedure-related complications. Choroidal melanomas demonstrated high stiffness values (58.4 ± 12.1 kPa), choroidal hemangiomas showed low stiffness (18.9 ± 6.4 kPa), metastases exhibited heterogeneous stiffness profiles (32.6 ± 9.8 kPa), and retinoblastoma showed intermediate stiffness (41.2 kPa). A shear-wave elastography cutoff of 28 kPa achieved a sensitivity of 91.6% and a specificity of 100% for malignancy discrimination, with excellent interobserver agreement (intraclass correlation coefficient = 0.91). These findings indicate that OcUsE is a safe, feasible, and reproducible technique that provides quantitative biomechanical information and may enhance the differentiation of benign and malignant intraocular tumors, supporting further validation in larger prospective studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.