ArticleCureus2026
Unmasking a High-Grade Malignant Neoplasm: A Rare Case of Small Bowel Melanoma.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant melanoma of the small bowel is a rare form of gastrointestinal malignancy. This case report describes a 70-year-old woman who presented with symptomatic iron deficiency anemia, progressive abdominal pain, weight loss, and other nonspecific symptoms, prompting an extensive diagnostic workup. Initial endoscopic evaluations were unremarkable, leading to further investigations, including capsule endoscopy and radiologic studies, which identified a jejunal mass. Histopathological and immunohistochemical analyses confirmed the diagnosis of malignant melanoma, and molecular testing identified a BRAF V600 mutation. The patient subsequently underwent surgical resection. This case highlights the diagnostic challenges of small bowel melanoma and the importance of comprehensive clinical, histopathological, and molecular evaluation in establishing the diagnosis. Given the aggressive nature of this malignancy, early diagnosis and timely intervention are essential for improving patient outcomes.
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