ArticleCureus2026
Microbiological Profile and Antimicrobial Resistance in Intensive Care Unit Patients With Sepsis and Septic Shock: A Prospective Single-Center Study From a Tertiary Care Intensive Care Unit.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Background Sepsis and septic shock remain the major causes of mortality in intensive care units (ICUs), increasingly complicated by antimicrobial resistance. However, microbiological profiles and resistance patterns vary widely across regions, and data from North African ICUs remain limited. This study aimed to describe the distribution of pathogens according to infection site, to analyze antimicrobial susceptibility patterns, and to assess the burden of multidrug-resistant organisms among ICU patients with sepsis and septic shock. Methods We conducted a prospective observational study in a mixed medical-surgical ICU at Ibn Rochd University Hospital, Casablanca, Morocco, over a 30-month period (January 2023-June 2025). Adult patients with sepsis or septic shock, defined according to Sepsis-3 criteria, were included. Microbiological analysis was restricted to patients with at least one clinically significant isolate, and only the first isolate per infectious episode was considered. Data included infection sites, pathogen distribution, antimicrobial resistance profiles, and ICU mortality. Results Eighty patients were included, yielding 192 microbiological samples, of which 126 (65.6%) were positive, corresponding to 142 clinically significant isolates. Polymicrobial infections were identified in 22/80 patients (27.5%). Gram-negative bacteria predominated overall, with
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