ArticleCureus2026
Clinical Profile, Organ Dysfunction Patterns, and Outcomes in Paraquat Poisoning: A Retrospective Analysis.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParaquat is a highly toxic herbicide associated with high mortality following acute ingestion, particularly in rural agricultural regions of India where it remains readily available.
objectiveTo characterize the clinical profile and organ dysfunction patterns of acute paraquat poisoning and to describe their relationship with in-hospital mortality outcomes in a rural tertiary care setting.
methodsThis retrospective observational study included adults admitted with acute oral paraquat ingestion at a tertiary care hospital in South India between August 2020 and August 2025. Demographic data, clinical features, organ involvement, treatment modalities, and outcomes were analyzed.
resultsTwenty-seven patients were included (mean age, 33.4 ± 15.1 years; 20 males (74.1%)). All ingestions were intentional (27/27, 100%). Multiorgan involvement was common, with respiratory failure in 25 patients (92.6%), acute kidney injury in 21 (77.8%), circulatory failure in 20 (74.1%), and hepatic dysfunction in nine (33.3%). Overall in-hospital mortality was 20/27 (74.1%). Mortality increased progressively with the cumulative number of dysfunctional organ systems: no deaths occurred among patients with isolated single-organ dysfunction (0/4, 0%), mortality was three of six (50%) in those with two-organ involvement, and all patients with dysfunction of three or more organ systems did not survive in this cohort (17/17, 100%). Age, gender, and time to hospital presentation were not significantly associated with survival.
conclusionAcute paraquat poisoning is associated with severe multisystem toxicity and high mortality. Mortality increased markedly with increasing organ dysfunction burden, with uniformly fatal outcomes once three or more organ systems were involved. Early hemoperfusion, although unavailable at our center, has been associated with improved survival in prior studies. These findings underscore the need for improved institutional preparedness and consideration of strengthened regulatory measures in regions where paraquat remains widely accessible.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.