ArticleCureus2026
The Successful Use of Noninvasive Ventilation in Severe Asthma Exacerbation: A Case Report and Review of the Literature.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute exacerbations of bronchial asthma (AEBA) complicated by hypercapnic respiratory failure (RF) are traditionally managed with invasive mechanical ventilation (IMV) when medical therapy fails. However, IMV is associated with significant complications, including barotrauma, hemodynamic instability, and increased mortality. The role of noninvasive ventilation (NIV) in AEBA remains controversial due to the limited and inconsistent nature of the available evidence. We report the case of an 18-year-old female with a history of bronchial asthma who presented with severe AEBA and acute hypercapnic RF that was refractory to standard medical therapy, including bronchodilators, systemic corticosteroids, epinephrine, and magnesium sulfate. Arterial blood gas (ABG) analysis demonstrated respiratory acidosis, with a peak partial pressure of carbon dioxide (PaCO
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