Evidence map›Paper›PMID 42147449›Full record

ReviewFrontiers in ophthalmology2026

Application of imaging studies for orbital tumors: a practical review and representative cases.

César Fernández, J Matthew Debnam, Bita Esmaeli

Abstract readReview
In one paragraph

Review in Frontiers in ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

César FernándezOculoplastics Clinic, Department of Ophthalmology, Hospital Universitario Universidad Autónoma de Nuevo León, Monterrey, Mexico.
J Matthew DebnamDepartment of Neuroradiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States.
Bita EsmaeliOncologic Ophthalmic Plastic and Orbital Surgery, Houston, TX, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orbital imaging has undergone a significant transformation over the past few decades, evolving from basic radiographic techniques to sophisticated cross-sectional imaging modalities. Historically, conventional radiography was limited to visualizing only the bony structures of the orbit or radiodense foreign bodies, making it inadequate for detecting soft tissue pathology. Advances in imaging over the last several decades-first with computed tomography (CT) in the 1970s and later with magnetic resonance imaging (MRI) in the 1980s-have revolutionized orbital diagnostics by enabling detailed visualization of both osseous and soft tissue structures. Magnetic resonance imaging (MRI) has emerged as the preferred modality for evaluating orbital tumors and other soft tissue lesions. Its superior soft tissue resolution, multiplanar imaging capability, and ability to characterize lesion morphology and extent make it crucial in clinical practice. MRI is especially valuable in differentiating benign from malignant lesions, evaluating involvement of critical structures such as the globe, optic nerve, extraocular muscles, and vascular components, and assessing disease at the orbital apex or with suspected intracranial extension. Advanced MRI techniques, including diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) MRI, further enhance diagnostic accuracy. In pediatric populations, MRI holds particular importance due to its lack of ionizing radiation and its effectiveness. In contrast, while CT offers superior resolution of bony anatomy and is useful for detecting calcifications and fractures, it is somewhat limited in soft tissue differentiation and involves exposure to ionizing radiation. While CT examination can be tailored to evaluate bone or soft tissues, orbital CT is typically reserved for cases requiring detailed osseous assessment, acute trauma settings, or for patients who cannot undergo an MRI. MRI creates high-resolution images by detecting signals emitted by hydrogen nuclei when exposed to a strong magnetic field and radiofrequency pulses. Differences in signal based on tissue composition and water content are captured and converted into high-resolution images. Interpreting orbital lesions requires standardized terminology.

Indexed as

lacrimal gland tumorsocular adnexal lymphomaorbital lymphomaorbital rhabdomyosarcomaorbital tumorspleomorphic adenoma of lacrimal glandsecondary tumors of orbit

Identifiers

PMID42147449
PMCPMC13171307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.