Evidence map›Paper›PMID 42147431›Full record

ArticleGastroenterology report2026

Ligation site of the inferior mesenteric vein in laparoscopic radical resection of rectal cancer: a study protocol for a multicenter randomized-controlled trial.

Shidong Hu, Songyan Li, Yang Yan, Lin Hua, Yi Xiao, Tao Li, Xiaohui Du

Abstract read
In one paragraph

Article in Gastroenterology report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shidong HuSenior Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, P. R. China.
Songyan LiSenior Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, P. R. China.
Yang YanSenior Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, P. R. China.
Lin HuaDepartment of Mathematics, School of Biomedical Engineering, Capital Medical University, Beijing, P. R. China.
Yi XiaoDivision of Colorectal Surgery, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P. R. China.ORCID https://orcid.org/0000-0002-4309-1227
Tao LiDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, P. R. China.
Xiaohui DuSenior Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The optimal level of ligation of the inferior mesenteric vein (IMV) during rectal cancer surgery remains unclear. Lymph nodes are distributed at the root of the IMV, but whether root ligation and lymphadenectomy significantly increase the number of lymph nodes harvested or improve patient prognosis remains unclear. This multicenter randomized-controlled trial was designed to compare long-term survival and short-term outcomes (surgical complications, lymph node yield, postoperative recovery) between high and low IMV ligation during laparoscopic radical rectal cancer resection. Methods: This multicenter randomized-controlled trial will enroll 1,516 patients undergoing laparoscopic-assisted radical resection for rectal cancer. Participants will be recruited and randomized (1:1) by using a dynamic minimization algorithm to balance covariates, including age, sex, American Society of Anesthesiologists classification, tumor location, body mass index, preoperative clinical stage, and neoadjuvant therapy. Patients will be allocated to either high ligation or low ligation of the IMV. The primary endpoint is 3-year disease-free survival. Discussion: The IMV ligation level is a critical yet controversial step in radical rectal cancer resection. High-level evidence is lacking regarding whether high IMV ligation improves rectal cancer prognosis, necessitating robust evidence to determine the optimal ligation level. Trial registration: ChiCTR, ChiCTR2300069149. Registered 8 March 2023, https://www.chictr.org.cn/showproj.html? proj=187562.

Indexed as

inferior mesenteric veinlymph nodesprognosisrectal cancersurgery

Identifiers

PMID42147431
PMCPMC13175179

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.