Evidence map›Paper›PMID 42147380›Full record

ArticleCase reports in ophthalmological medicine2026

Deep Anterior Lamellar Keratoplasty on a Descemet's Membrane Endothelial Keratoplasty Graft: A Case Report.

Yuto Yukari, Takahiko Hayashi, Satoru Yamagami

Abstract read
In one paragraph

Article in Case reports in ophthalmological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuto YukariDepartment of Ophthalmology, Nihon University Itabashi Hospital, Tokyo, Japan, nihon-u.ac.jp.ORCID https://orcid.org/0009-0006-9928-4892
Takahiko HayashiDepartment of Ophthalmology, Nihon University Itabashi Hospital, Tokyo, Japan, nihon-u.ac.jp.ORCID https://orcid.org/0000-0001-8704-680X
Satoru YamagamiDepartment of Ophthalmology, Nihon University Itabashi Hospital, Tokyo, Japan, nihon-u.ac.jp.ORCID https://orcid.org/0000-0002-1330-5386

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Deep anterior lamellar keratoplasty (DALK) has been reported in eyes following Descemet's stripping automated endothelial keratoplasty (DSAEK); however, its application after Descemet's membrane endothelial keratoplasty (DMEK) has not been reported. Case Presentation: The patient was an 87-year-old woman who underwent repeat DMEK for late DMEK graft failure that had healed with corneal haze due to long-term endothelial dysfunction. DALK was then performed to remove opacity and improve corneal irregular astigmatism. The corneal epithelium and stroma were removed via manual dissection to the pre-Descemet's layer. Discussion: This case demonstrates that DALK can be safely performed after DMEK to treat stromal opacity and irregular astigmatism, with favorable visual and anatomical outcomes. Therapeutic DALK and prophylactic antifungal eye drops effectively treated the fungal infection and recurrence was not observed. This case highlights the clinical feasibility of staged keratoplasty and suggests that DALK may be considered a viable option for managing stromal opacity even after endothelial keratoplasty. These findings may contribute to expanding the surgical indications of DALK in complex corneal cases following endothelial keratoplasty.

Indexed as

corneal irregular astigmatismdeep anterior lamellar keratoplastyDescemet′s membrane endothelial keratoplastytherapeutic keratoplasty

Identifiers

PMID42147380
PMCPMC13176624

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.