Evidence map›Paper›PMID 42147355›Full record

ArticleCancer communications (London, England)2026

Targeting Grade-Specific Endoplasmic Reticulum Stress Vulnerabilities in Chondrosarcoma: Divergent Roles of Protein Kinase R-Like Endoplasmic Reticulum Kinase and Inositol-Requiring Enzyme 1α Signaling.

Hongtai Chen, Zezhuo Su, Ying Lee Lam, Raymond Ching Hin Yau, Anderson Siu Ming Leung, Gabriel Ching Ngai Leung, John Robert Honiball, Richard O C Oreffo, Jason Pui Yin Cheung, Siu Wai Choi and 1 more

Abstract readLetter
In one paragraph

Article in Cancer communications (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongtai ChenDepartment of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-3291-120X
Zezhuo SuDepartment of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0001-5915-1602
Ying Lee LamOrthopaedic Oncology and Limb Salvage Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-6911-3017
Raymond Ching Hin YauOrthopaedic Oncology and Limb Salvage Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-5508-4622
Anderson Siu Ming LeungOrthopaedic Oncology and Limb Salvage Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-0403-5847
Gabriel Ching Ngai LeungOrthopaedic Oncology and Limb Salvage Surgery, Department of Orthopaedics and Traumatology, Queen Mary Hospital, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0003-4702-4088
John Robert HoniballDepartment of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0009-0007-2894-4213
Richard O C OreffoBone and Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, University of Southampton, Southampton, UK.ORCID https://orcid.org/0000-0001-5995-6726
Jason Pui Yin CheungDepartment of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-7052-0875
Siu Wai ChoiDepartment of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-8189-790X
Kelvin Sin Chi CheungDepartment of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.ORCID https://orcid.org/0000-0002-1562-8883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42147355
PMCPMC13172731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.