Evidence map›Paper›PMID 42147283›Full record

ArticleFrontiers in plant science2026

Regulation of gene expression by 5mC DNA methylation during the bolting process of cabbage (

Huiling Guo, Xinyu Chen, Bin Zhang, Xuehui Yao, Mu Zhuang, Limei Yang, Jialei Ji, Yong Wang, Honghao Lv, Yangyong Zhang

Abstract read
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In one paragraph

Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huiling Guo *State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Xinyu Chen *State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Bin ZhangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Xuehui YaoState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Mu ZhuangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Limei YangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Jialei JiState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Yong WangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Honghao LvState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.
Yangyong ZhangState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is an essential epigenetic modification. However, the dynamics of DNA methylation during cabbage bolting remain poorly understood. To investigate changes in DNA methylation during cabbage bolting, we performed whole-genome bisulfite sequencing (WGBS) on both vegetative leaves of non-bolting plants and reproductive leaves of bolting plants in two cabbage accessions. Across the whole genome, the DNA methylation levels on each chromosome showed a negative correlation with gene density, and the methylation levels in reproductive leaves after bolting were higher than those in vegetative leaves before bolting. We identified a total of 10,159 differentially methylated regions (DMRs). GO enrichment analysis revealed that differentially methylated genes were significantly enriched in pathways related to reproductive process and floral organ development. At the subgenome level, MF2 exhibited a higher DNA methylation advantage, and the dominance of all three subgenomes was greater in reproductive leaves than in vegetative leaves. Integrating the transcriptomic data, we found that genes with DNA methylation modifications showed markedly lower expression levels than those without methylation. Two meristem-development-related genes,

Indexed as

boltingcabbageDNA methylationreproductiveWGBS

Identifiers

PMID42147283
PMCPMC13171550

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