Evidence map›Paper›PMID 42147269›Full record

ArticleRegenerative biomaterials2026

Calcium, cobalt, strontium and cerium-based binary silicate bioactive nanoglasses: rational comparison in bioactive properties for optimizing tissue repair applications.

Yanzi Zhao, Jing Tian, Liuyang Zhang, Long Zhang, Qian Huang, Xiaoyan Qu, Bo Lei

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanzi ZhaoKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an 710054, China.
Jing TianFrontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710054, China.
Liuyang ZhangFrontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710054, China.
Long ZhangDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Qian HuangKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an 710054, China.
Xiaoyan QuFrontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710054, China.
Bo LeiKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an 710054, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silicate bioactive glass nanoparticles (SBGNs) are promising for tissue repair, but multi-metals doped systems often suffer from compositional complexity, undefined ion-function relationships, and insufficient mechanistic validation. Herein, we established a compositionally simplified binary platform and synthesized four single-ion doped SBGNs (MBGNs: BCa, BCo, BSr, BCe) incorporating representative alkaline-earth, transition, and rare-earth elements. Their tissue repair-relevant bioactivities were systematically compared under unified synthesis and evaluation conditions. All MBGNs exhibited good cytocompatibility but displayed distinct, element-dependent bioactivity profiles. BCa enhanced baseline bioactivity by promoting apatite nucleation in simulated body fluid. BSr showed the strongest anti-inflammatory activity, reducing

Indexed as

bioactive glass nanoparticlesbioactive materialsion dopingwound repair

Identifiers

PMID42147269
PMCPMC13176458

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.