ArticleWorld journal of oncology2026
Detection of Longer Leukocyte Telomere Length in Patients With Bone Sarcomas.
Article in World journal of oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bone sarcomas are rare and heterogeneous malignant neoplasms of mesenchymal origin, often associated with poor clinical outcomes. Being rare neoplasms, a comprehensive analysis of the molecular mechanisms involved in the tumor biology of bone sarcomas is still lacking. Telomeres are repetitive nucleotide sequences (TTAGGG)n at chromosome ends playing an essential role in genome stability, and their dysfunction has been associated with several human diseases, including cancer. This study aimed to assess telomere dynamics in pediatric and adult patients with bone sarcomas. Methods: The measurements of relative telomere length (RTL) in peripheral blood leukocytes were evaluated by quantitative polymerase chain reaction (qPCR) in 44 patients with newly diagnosed, histologically confirmed, treatment-naive bone sarcomas. The control group comprised 50 cancer-free individuals. Results: Overall, we observed significantly longer RTL in patients compared to controls (P = 0.02). RTL was also significantly longer in male patients compared to male controls (P = 0.01). Among patients, no significant association was observed between RTL and age group (pediatric vs. adult), sex (male vs. female), and outcome events (recurrence, metastasis or death). Conclusions: Our findings indicate that longer leukocyte telomere length in patients, compared with cancer-free controls, may be associated with increased susceptibility to bone sarcoma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.