Evidence map›Paper›PMID 42147194›Full record

ArticleResearch square2026

CDCP1 Deletion Protects Against Pressure Overload-Induced Cardiac Dysfunction and Fibrosis in Mice.

Naveen Pereira, Rachad Ghazal, Akshatha N Srinivas, Min Wang, Jenny Jia Ling Cao, Li Wang, Irene Marín-Goñi, William Sherman, August John, Hridyanshu Vyas and 13 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Naveen PereiraMayo Clinic.
Rachad GhazalMayo Clinic.
Akshatha N SrinivasMayo Clinic.
Min WangMayo Clinic.
Jenny Jia Ling CaoDepartment of Cardiovascular Diseases, Mayo Clinic.
Li WangMayo Clinic.
Irene Marín-GoñiMayo Clinic.
William ShermanMayo Clinic.ORCID 0000-0002-6823-487X
August JohnMayo Clinic.
Hridyanshu VyasMayo Clinic.
Carolyn RoosMayo Clinic.
Runqing HuangMayo Clinic.
Tamas OrdogMayo Clinic.ORCID 0000-0002-3940-7284
Chen WangMayo Clinic.ORCID 0000-0003-2638-3081
Christy TrussoniMayo Clinic.
Do Young LimMayo Clinic.
Darren BakerMayo Clinic.ORCID 0000-0001-9006-1939
Gianfranco SinagraOspedali Riuniti and University of Trieste.
Richard WeinshilboumMayo Clinic.ORCID 0000-0002-4911-7985
Duan LiuMayo Clinic.ORCID 0000-0003-1065-246X
Laura J LambertMayo Clinic.
Jordan MillerMayo Clinic.
Daniel TschumperlinMayo Clinic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human genomic studies link reduced CUB domain-containing protein 1 (CDCP1) expression with myocardial recovery in heart failure. While CDCP1 regulates cardiac fibroblast proliferation in vitro, it's in vivo role in cardiac fibrosis remains unclear. Using a

Indexed as

cardiac fibrosisCDCP1heart failuremouse modelspatial transcriptomics

Identifiers

PMID42147194
PMCPMC13174822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.