Evidence map›Paper›PMID 42147033›Full record

ReviewFrontiers in genome editing2026

Reconstructing the complex architecture of the genome with molecular scissors: applying genome editing technology in precision medicine.

Md Nur Amin Khan, Rohit Das, Pooja Barik, Somasundaram Arumugam, Shiladitya Chattopadhyay

Abstract readReview
In one paragraph

Review in Frontiers in genome editing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Md Nur Amin Khan *Department of Biopharmaceuticals, National Institute of Pharmaceutical Education and Research Kolkata (NIPER Kolkata), Kolkata, India.
Rohit Das *Department of Biopharmaceuticals, National Institute of Pharmaceutical Education and Research Kolkata (NIPER Kolkata), Kolkata, India.
Pooja BarikDepartment of Biopharmaceuticals, National Institute of Pharmaceutical Education and Research Kolkata (NIPER Kolkata), Kolkata, India.
Somasundaram ArumugamDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Kolkata (NIPER Kolkata), Kolkata, India.
Shiladitya ChattopadhyayDepartment of Biopharmaceuticals, National Institute of Pharmaceutical Education and Research Kolkata (NIPER Kolkata), Kolkata, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our past, present, and future are governed by the grand design of the genetic blueprint, which was mapped more than two decades back. While the eloquent design of our genome results from millions of years of evolution and has reached a near-perfect stage, unwanted flaws and mistakes in individual genomes can make their life miserable and worth intervention. The advent of technologies to manipulate the grand design and make it congenial for the individual has given new hope. Here, we discuss how gene editing technologies have progressed and how some of the technologies have become indispensable gears in precision medicine.

Indexed as

CRISPRgenome editingprecision medicineTALENZFN

Identifiers

PMID42147033
PMCPMC13171518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.