Trial reportFrontiers in pediatrics2026
Erector spinae plane block for opioid sparing in children undergoing laparoscopic appendectomy: a randomized controlled trial.
Trial report in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Despite being a minimally invasive procedure, laparoscopic appendectomy (LA) frequently induces substantial postoperative pain in children. While erector spinae plane block (ESPB) has demonstrated efficacy for postoperative analgesia in pediatric open abdominal surgery, its analgesic benefits and safety profile in laparoscopic procedures remain unestablished. Purpose: To evaluate the opioid-sparing effects, analgesic efficacy, and safety of ESPB in children undergoing LA. Design: A single-center, double-blind, randomized, superiority trial. Methods: Children aged 6-12 years with American Society of Anesthesiologists (ASA) physical status I-II scheduled for LA at Anhui Provincial Children's Hospital were enrolled. Participants were randomly allocated 1:1 using a computer-generated sequence to receive either bilateral ultrasound-guided ESPB at T8 (0.25% ropivacaine, 0.5 mL/kg per side) after tracheal intubation (ESPB group) or no block (Control group). Both groups received standardized multimodal analgesia comprising hydromorphone-based patient-controlled intravenous analgesia (PCIA) and scheduled acetaminophen. The primary outcome was 0-24 h cumulative hydromorphone consumption; secondary outcomes included pain scores, PCIA parameters, rescue analgesia requirements, recovery milestones, parental satisfaction, and adverse events. Results: Of the 80 children randomized (40 per group), 75 completed follow-up and were analyzed (ESPB, Conclusions: In children undergoing LA, a single-injection bilateral ultrasound-guided ESPB at T8 provides significant opioid-sparing effects and alleviates acute postoperative pain during the first 24 h without increasing adverse event rates, supporting its incorporation as a component of multimodal analgesia for postoperative pain management in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.