Evidence map›Paper›PMID 42146924›Full record

ArticleFrontiers in pediatrics2026

Age

Mengzhen Zhang, Qirui Liu, Hao Wei, Ailian Wang, Jiaoyan Wang, Hai Li, Xueling Jing

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengzhen Zhang *Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Si Chuan, China.
Qirui Liu *Department of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Si Chuan, China.
Hao WeiDepartment of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Si Chuan, China.
Ailian WangDepartment of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Si Chuan, China.
Jiaoyan WangDepartment of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Si Chuan, China.
Hai LiDepartment of Pediatrics, Affiliated Hospital of North Sichuan Medical College, Si Chuan, China.
Xueling JingDepartment of Pediatrics, People's Hospital of Nanbu County, Nanchong, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to evaluate whether Methods: We conducted a retrospective cohort study of children with Results: A total of 150 children were enrolled, with 13 in the macrolide resistance gene-negative group and 137 in the positive group, resulting in a macrolide resistance gene positivity rate of 91.3%. Of these patients Conclusion: In the Nanchong area, macrolide resistance mediated by the 23S rRNA A2063G mutation predominates. Resistance gene detection alone indicates only potential resistance but cannot independently guide antibiotic switching. Among gene-positive children, elevated CRP and older age are early predictors of switching need, while prolonged hospital stay serves as a retrospective confirmatory marker. Clinical decisions should integrate these biomarkers rather than relying solely on genetic results.

Indexed as

ageazithromycinc-Reactive proteindoxycyclinehospital staymacrolide-resistant mycoplasma pneumoniaepredictive factorresistance gene

Identifiers

PMID42146924
PMCPMC13171521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.