Evidence map›Paper›PMID 42146848›Full record

ArticleIEEE journal of translational engineering in health and medicine2026

Innovative Wearable Platform for Synchronized Biosignals Acquisition: A Proof of Concept in a Cuff-Less Blood Pressure Monitoring Case Study.

Alessio Serrani, Andrea Aliverti

Abstract read
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Article in IEEE journal of translational engineering in health and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Alessio SerraniDipartimento di ElettronicaInformazione e BioingegneriaPolitecnico di Milano Milan 20133 Italy.ORCID 0009-0004-8893-9836
Andrea AlivertiDipartimento di ElettronicaInformazione e BioingegneriaPolitecnico di Milano Milan 20133 Italy.ORCID 0000-0002-2950-0231

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluates the performance of a fully wireless multi-node wearable platform equipped with a sub-microsecond synchronization engine in a clinically relevant scenario. The prototype system is used in a cuff-less blood pressure monitoring application, based on pulse arrival time derived from synchronized ECG and PPG signals.

methodsThe system integrates a custom 2.4 GHz synchronization protocol and Bluetooth Low Energy for data transmission. Nineteen healthy subjects completed a treadmill protocol designed to induce transient hemodynamic perturbations representative of daily-life physical activities. PAT values extracted from ECG and PPG signals acquired before and after exercise were compared with reference systolic blood pressure (SBP) measurements, intermittently sampled using a validated oscillometric device. The experimental protocol and analysis were designed to reflect realistic home monitoring scenarios, including limited user interaction during measurements.

resultsImmediately after exercise, significant deviations from baseline were observed in computed PAT ([Formula: see text]) and SBP ([Formula: see text]). PAT recovery trend was accurately modeled by a mono-exponential function ([Formula: see text]). Recovery indices derived from PAT and SBP were strongly correlated (Pearson's [Formula: see text], [Formula: see text]) with high concordance ([Formula: see text]), although Bland-Altman analysis revealed subject-specific variability (LoA: -34.36% / 37.53%).

conclusionThe proposed platform enables continuous synchronized multi-signal acquisition for extracting PAT dynamics and tracking blood pressure fluctuations under realistic home-monitoring conditions, with minimal additional user interaction. These results support the operational feasibility of wirelessly synchronized architectures for cardiovascular monitoring in daily-life scenarios, promoting integration into remote health assessment workflows beyond traditional intermittent cuff-based measurements.

Indexed as

Blood Pressure DeterminationSignal Processing, Computer-AssistedWearable Electronic DevicesAdultBlood PressureElectrocardiographyEquipment DesignFemaleHumansMaleProof of Concept StudyWireless TechnologyYoung AdultCardiovascular dynamicscuff-less blood pressure monitoringimproving comfort and long-term adherencepulse arrival timewireless wearable platform.Clinical Impact—The proposed fully wireless platform can support clinicians in tracking cardiovascular dynamics outside clinical environments and helps patients undergo unobtrusive monitoring during daily life

Identifiers

PMID42146848
PMCPMC13175598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.