ArticleAnnals of gastroenterological surgery2026
Association Between Liver Function Grade and Post-Hepatectomy Liver Failure in Patients With Hepatocellular Carcinoma: A Latent Class Analysis.
Article in Annals of gastroenterological surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Mac-2 Binding Protein Glycosylation Isomer (M2BPGi)-Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma.Annals of gastroenterological surgery · 2026Article
- Association Between Liver Function Grade and Post-Hepatectomy Liver Failure in Patients With Hepatocellular Carcinoma: A Latent Class Analysis.Annals of gastroenterological surgery · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, with post-hepatectomy liver failure (PHLF) representing a major complication. We aimed to develop an objective, multidimensional liver function grading system via latent class analysis (LCA) and assess its predictive value for PHLF in combination with surgical parameters. Methods: Among 185 HCC patients who underwent resection, the LCA incorporated nine liver function indicators, including severity of liver cirrhosis, splenomegaly, platelet count (PLT), etc., to categorize liver function into three grades: poor, intermediate, and good. Discrimination was evaluated using entropy. Restricted cubic spline analysis assessed the association between blood loss and PHLF, and multivariate logistic regression identified independent predictors. Results: LCA yielded three distinct classes (entropy = 0.953). Blood loss showed a nonlinear relationship with PHLF ( Conclusion: This LCA-based grading system, integrating imaging and biochemical markers, enables precise PHLF risk stratification and, combined with surgical variables, may inform individualized perioperative management in HCC resection.
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