ArticleSage open pediatrics
Resting-State Functional Connectivity Alterations in Pediatric Survivors of Severe COVID-19: An Exploratory Case-Control Study.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To assess resting-state functional connectivity and exploratory cognitive vulnerability in pediatric survivors of severe COVID-19 compared with healthy pre-pandemic controls. Introduction: Pediatric neurocognitive sequelae after SARS-CoV-2 infection remain poorly characterized. Methods: We conducted an observational case-control study including 14 children hospitalized for severe COVID-19 and 31 healthy pre-pandemic controls scanned on the same 3T MRI system using identical rs-fMRI protocols and a standardized CONN/SPM pipeline. ROI-to-ROI connectivity was analyzed with cluster-level FDR correction ( Results: Post-COVID participants showed 3 altered connectivity clusters: increased Default Mode-visual medial coupling, stronger dorsal attention-sensorimotor anticorrelations, and enhanced temporo-occipital-vermis connectivity. In an exploratory subset (8 post-COVID, 12 controls), 50% of post-COVID children had abnormally low Timeliness and 25% low Impulsivity MOXO-d-CPT Conclusion: These preliminary findings suggest subtle post-infectious cognitive vulnerability and warrant confirmation in larger longitudinal cohorts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.