ArticleACS materials Au2026
Biocompatible Self-Healing Hydrogel for VAT 3D Printing.
Article in ACS materials Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Self-healing hydrogels (SHHs) are promising materials in tissue engineering due to their ability to mimic the biomechanical properties of biological tissues and autonomously repair damage and can serve as ideal three-dimensional scaffolds for cell proliferation and differentiation. However, conventional processing methods, such as extrusion-based printing, often limit the complexity and resolution of the fabricated structures. VAT photopolymerization, particularly digital light processing (DLP), on the other hand, offers advantages in terms of resolution, printing speed, and design freedom, making it an attractive approach for developing SHHs. This study aims to develop a biocompatible and self-healing hydrogel through DLP, enhancing the structural complexity while maintaining self-repairing properties. The hydrogel is made from polyethylene glycol diacrylate (PEGDA), hydroxyethyl methacrylate (HEMA), dithiothreitol (DTT), and borax, and the solvent is PBS. Cross-linking occurs by radical photopolymerization, in which PEGDA and HEMA serve as cross-linkable monomers, while DTT and borax form borate-ester bonds, imparting self-repairing properties. Complex 3D structures were fabricated by using a commercial DLP printer, and self-healing properties were assessed. Chemical (FTIR, NMR), rheological, and mechanical analyses were performed along with cytocompatibility tests. The hydrogel exhibited successful 3D printability, allowing the fabrication of complex structures. Self-healing tests demonstrated that, after 72 h, the samples could self-repair and withstand tensile forces, maintaining their integrity after multiple damage-repair cycles. Chemical and mechanical characterization confirmed the stability and viscoelastic behavior of the material, while preliminary cytocompatibility assays indicated the suitability for tissue engineering applications. DLP-based printing enables the fabrication of self-healing hydrogels with improved resolution and design freedom. The developed hydrogel exhibits promising mechanical properties and biocompatibility, making it a strong candidate for tissue engineering applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.