Evidence map›Paper›PMID 42146694›Full record

ArticlebioRxiv : the preprint server for biology2026

Reactivation of a TAL1 progenitor cell enhancer region by non-coding somatic variants in T-lineage acute lymphoblastic leukemia.

Nadezhda V Terekhanova, Xiaolong Chen, Kin-Hoe Chow, Yu Liu, Ying Shao, Li Dong, Bensheng Ju, Vinesh Vinayachandran, Haseeb Zubair, Kohei Hagiwara and 7 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nadezhda V TerekhanovaDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Xiaolong ChenDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Kin-Hoe ChowDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA.
Yu LiuDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Ying ShaoDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Li DongDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Bensheng JuDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Vinesh VinayachandranDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Haseeb ZubairDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Kohei HagiwaraDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Wentao YangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Xiaotu MaDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Sivaraman NatarajanDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
John EastonDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
David T TeacheyPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
A Thomas LookDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA.
Jinghui ZhangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
COG U24 Funding 2026-2027U24CA196173 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Mignon Lee-Cheun Loh, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$62.5M
Discovery of Somatic Noncoding Variants that Serve as Drivers in Pediatric CancersR01CA216391 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI ZHANG, JINGHUI · 2018 to 2022
$2.8M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA216391NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NCI NIH HHS U24 CA196173
6 · The paper itself

Abstract

Aberrant activation of

Identifiers

PMID42146694
PMCPMC13174455

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.