Evidence map›Paper›PMID 42146686›Full record

ArticlebioRxiv : the preprint server for biology2026

Disruption of the AgMOBP1-PfSyn5 interface abolishes malaria transmission.

Julian Ramelow, Guodong Niu, Luka Kostallas, Liliana Lai, Xiaohong Wang, Jun Li

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julian RamelowHerbert Wertheim College of Medicine, Biomedical Sciences Graduate Program, Florida International University, Miami, FL 33199, United States.
Guodong NiuDepartment of Biological Sciences, Florida International University, Miami, FL 33199, United States.
Luka KostallasDepartment of Biochemistry, Undergraduate Program, Florida International University, Miami, FL 33199, United States.
Liliana LaiDepartment of Biological Sciences, Florida International University, Miami, FL 33199, United States.
Xiaohong WangDepartment of Biological Sciences, Florida International University, Miami, FL 33199, United States.
Jun LiHerbert Wertheim College of Medicine, Biomedical Sciences Graduate Program, Florida International University, Miami, FL 33199, United States.ORCID 0000-0002-2121-3393

Funding

Fungal metabolites block malaria transmissionR01AI125657 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI LI, JUN · 2017 to 2021
$2.5M
Plasmodium and Anopheles midgut interactive proteins influence malaria transmissionR01AI179943 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI Jun Li · 2025 to 2026
$1.4M
NIAID NIH HHS R01 AI125657NIAID NIH HHS R01 AI179943
6 · The paper itself

Abstract

Malaria control remains constrained by an incomplete understanding of the molecular interactions that enable

Indexed as

AGAP008138Anopheles gambiaehost–parasite interactionmalaria interventionmalaria transmissionmosquito midgutPfSyn5Plasmodium falciparumtransmission-blocking vaccinevector biology

Identifiers

PMID42146686
PMCPMC13174592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.