Evidence map›Paper›PMID 42146659›Full record

ArticlebioRxiv : the preprint server for biology2026

Coincident epithelial signals restrain commensal-specific CD8αβ

Tayla M Olsen, Matthew J Dufort, Sheenam Verma, Venkata Krishna Kanth Makani, Benjamin Cameron, Addison R Gralen, Aaron J Johnson, Alok V Joglekar, Allyson L Byrd, Adam Lacy-Hulbert and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tayla M OlsenGut Immunity Research Program, Benaroya Research Institute, Seattle, WA, USA.
Matthew J DufortCenter for Systems Immunology, Benaroya Research Institute, Seattle, WA, USA.
Sheenam VermaGut Immunity Research Program, Benaroya Research Institute, Seattle, WA, USA.
Venkata Krishna Kanth MakaniCenter for Systems Immunology and the Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Benjamin CameronCenter for Systems Immunology and the Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Addison R GralenGut Immunity Research Program, Benaroya Research Institute, Seattle, WA, USA.
Aaron J JohnsonNeuroscience Program, Mayo Clinic, Rochester, MN, USA.
Alok V JoglekarCenter for Systems Immunology and the Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Allyson L ByrdGut Immunity Research Program, Benaroya Research Institute, Seattle, WA, USA.
Adam Lacy-HulbertGut Immunity Research Program, Benaroya Research Institute, Seattle, WA, USA.
Oliver J HarrisonGut Immunity Research Program, Benaroya Research Institute, Seattle, WA, USA.ORCID 0000-0003-1515-9586

Funding

Training in Cellular & Molecular BiologyT32GM136534 · NIGMS · UNIVERSITY OF WASHINGTON · PI Andrew Atwell Oberst, LARRY S ZWEIFEL · 2021 to 2026
$5.8M
Commensal-specific T cell function in skin wound repairR01AI158624 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI HARRISON, OLIVER JAMES · 2021 to 2025
$2.9M
Regulation of TLR signaling in anti-commensal B cell responses and mucosal inflammationR21AI171921 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI HARRISON, OLIVER JAMES, LACY-HULBERT, ADAM · 2023 to 2024
$477k
Building tools to study commensal-specific CD8+ T cells in the small intestineR03AI190880 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI Oliver James Harrison · 2025 to 2026
$173k
NIAID NIH HHS R01 AI158624NIAID NIH HHS R03 AI190880NIAID NIH HHS R21 AI171921NIGMS NIH HHS T32 GM136534
6 · The paper itself

Abstract

The intestinal epithelium harbors a large population of microbiota-dependent CD8αβ

Identifiers

PMID42146659
PMCPMC13174671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.