Evidence map›Paper›PMID 42146647›Full record

ArticlebioRxiv : the preprint server for biology2026

Probing RNA-protein interactions in the early mouse embryo.

Pablo Bora, Oliver J Rando

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pablo BoraDepartment of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA.
Oliver J RandoDepartment of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA.

Funding

Regulation of tRNA fragment biogenesis and function by nucleotide modificationsR01HD099816 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RANDO, OLIVER J · 2021 to 2025
$2.4M
NICHD NIH HHS R01 HD099816
6 · The paper itself

Abstract

The union of two germ cells to form a zygote, and subsequent early embryo development, are marked by radical remodeling of virtually every major class of biomolecules as the specialized germline states give way to the rapid and active growth that marks early development. In recent years, advances in ultra-low input genome-wide methods have enabled systematic analyses of mRNA abundance, and of chromatin organization, throughout early development in a variety of model systems. Here, we extend these efforts to the study of RNA binding protein (RBP) function in early mouse embryos, adapting REMORA

Identifiers

PMID42146647
PMCPMC13174668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.