Evidence map›Paper›PMID 42146608›Full record

ArticlebioRxiv : the preprint server for biology2026

An Nrf2-Nup214 positive feedback loop sustains the antioxidant response and promotes microbial infection in ticks.

Kaylee A Vosbigian, Chelsea A Osbron, Brianna P Steiert, Kristin L Rosche, Sarah J Wright, Elisabeth Ramirez-Zepp, Dana K Shaw

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaylee A VosbigianDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.ORCID 0000-0003-2865-7031
Chelsea A OsbronDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.ORCID 0000-0003-1210-9284
Brianna P SteiertDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.ORCID 0000-0002-7992-004X
Kristin L RoscheDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.ORCID 0009-0003-6127-4363
Sarah J WrightDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.ORCID 0009-0008-9766-4714
Elisabeth Ramirez-ZeppDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.
Dana K ShawDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164 USA.ORCID 0000-0002-5212-2494

Funding

TRAINING IN BIOTECHNOLOGY: EMPHASIS ON PROTEIN CHEMISTRYT32GM008336 · NIGMS · WASHINGTON STATE UNIVERSITY · PI CALL, DOUGLAS R. · 1989 to 2023
$8.9M
Infectious Diseases and Microbial Immunology Training ProgramT32AI007025 · NIAID · WASHINGTON STATE UNIVERSITY · PI Thomas H KAWULA, M KARIUKI NJENGA · 1985 to 2026
$7.4M
Tick-Pathogen Interactions: Exploring the Intersection between Stress Responses and ImmunityR01AI162819 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2022 to 2025
$2.0M
Motivating Innovation and Research Achievement (MIRA)R25EB027606 · NIBIB · WASHINGTON STATE UNIVERSITY · PI Samantha Gizerian, Alla S. Kostyukova · 2020 to 2026
$1.2M
TICK-PATHOGEN INTERFACE: INVESTIGATING CROSSTALK BETWEEN STRESS RESPONSES AND IMMUNITYR21AI139772 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2018 to 2019
$421k
Functional Impact of Stress Granules on Tick-Microbe InteractionsR21AI148578 · NIAID · WASHINGTON STATE UNIVERSITY · PI SHAW, DANA KATHLEEN · 2020 to 2021
$421k
NIAID NIH HHS R01 AI162819NIAID NIH HHS R21 AI139772NIAID NIH HHS R21 AI148578NIAID NIH HHS T32 AI007025NIBIB NIH HHS R25 EB027606NIGMS NIH HHS T32 GM008336
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42146608
PMCPMC13174655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.