Evidence map›Paper›PMID 42146598›Full record

ArticlebioRxiv : the preprint server for biology2026

Hydrocephalus caused by

Ana Limerick, Cheuk Ying Chu, Jacob S Turner, David L Brautigan, Wenhao Xu, Zheng Fu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana LimerickDepartment of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.
Cheuk Ying ChuDepartment of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.
Jacob S TurnerDepartment of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.
David L BrautiganDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia.
Wenhao XuDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia.
Zheng FuDepartment of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.ORCID 0000-0003-1238-6695

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Jay William FOX · 1987 to 2026
$72.1M
Signaling Mechanisms and Cellular Functions of a Ciliopathy-Associated Protein KinaseR01GM127690 · NIGMS · UNIVERSITY OF VIRGINIA · PI Zheng Fu · 2018 to 2026
$2.4M
NCI NIH HHS P30 CA044579NIGMS NIH HHS R01 GM127690
6 · The paper itself

Abstract

Background: Results: We produced a Conclusion: KATNIP loss of function gives rise to hydrocephalus found in Joubert syndrome. The results indicate that KATNIP restricts ciliogenesis and cilia extension and supports proliferation of neuroprogenitor cells in the brain.

Indexed as

brain developmentciliogenesisciliopathyneuroprogenitor cellsprimary cilia

Identifiers

PMID42146598
PMCPMC13174529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.