Evidence map›Paper›PMID 42146580›Full record

ArticlebioRxiv : the preprint server for biology2026

The Case for Kinases: A Phosphorylation Driven Model for Circadian Temperature Compensation.

Elizabeth-Lauren Stevenson, Christina M Kelliher, Arminja N Kettenbach, Jennifer J Loros, Jay C Dunlap

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth-Lauren StevensonDept. of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Christina M KelliherDept. of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Arminja N KettenbachDept. of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Jennifer J LorosDept. of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Jay C DunlapDept. of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH.

Funding

Genetic and Molecular Dissection of the Neurospora ClockR35GM118021 · NIGMS · DARTMOUTH COLLEGE · PI Jay C. Dunlap · 2016 to 2026
$7.3M
Phosphorylation Signaling by Phosphoprotein PhosphatasesR35GM119455 · NIGMS · DARTMOUTH COLLEGE · PI Arminja Nadine Kettenbach · 2016 to 2026
$5.1M
Deciphering metabolic and cellular effectors of nutritional compensation in the circadian clockR35GM157067 · NIGMS · UNIVERSITY OF MASSACHUSETTS BOSTON · PI Christina Kelliher · 2025 to 2026
$748k
Genetic and Molecular Dissection of Regulatory Mechanisms Underlying Temperature and Nutritional Compensation of the Circadian Clock in Neurospora crassaF32GM128252 · NIGMS · DARTMOUTH COLLEGE · PI KELLIHER, CHRISTINA · 2018 to 2022
$210k
Role of Phosphorylation in Determining Circadian Period Length and Temperature CompensationF31HL165774 · NHLBI · DARTMOUTH COLLEGE · PI STEVENSON, ELIZABETH-LAUREN · 2023 to 2025
$146k
NHLBI NIH HHS F31 HL165774NIGMS NIH HHS F32 GM128252NIGMS NIH HHS R35 GM118021NIGMS NIH HHS R35 GM119455NIGMS NIH HHS R35 GM157067
6 · The paper itself

Abstract

Circadian rhythms, ~24-hour biological cycles, enable organisms to anticipate rhythmic environmental cycles so they can assign proper day and night functions that align with those cycles. Circadian rhythms are defined by their ability to be reset by external cues, their capacity to continue to oscillate in the absence of those cues, and their capacity to maintain the rate of the clock across a range of ambient temperatures, a property known as temperature compensation. In the

Identifiers

PMID42146580
PMCPMC13174666

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.