ArticlebioRxiv : the preprint server for biology2026
Minding the gap: collective determinants of multiscale structure across interacting bacterial colonies.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
A bacterial colony rarely exists in isolation - in natural habitats, colonies interact to form spatially structured communities across length and time scales. Eco-evolutionary feedbacks link these scales, such that structure at one level can influence another, yet the interplay between single- and multi-colony organization remains poorly understood. As a step toward addressing this, we develop a high-throughput platform to track population dynamics across spatially extended networks of colonies. A common structural feature observed at the multi-colony scale is the formation of a stable gap region between colonies, even when they are isogenic. Numerous studies observe similar patterns of behavior across species, with few resolving the underlying mechanism. Here, we ask: what are the minimal ingredients shaping this multi-colony structure? We focus on colonies of the opportunistic pathogen
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