Evidence map›Paper›PMID 42146502›Full record

ArticlebioRxiv : the preprint server for biology2026

Photoreceptor outer segment disk rim curvature relies on a tetraspanin interaction web.

R Casey Boucher, Michelle L Milstein, Amirali Hossein, Breyanna L Cavanaugh, Alexander J Sodt, Andrew H Beaven, Andrew F X Goldberg

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

R Casey BoucherEye Research Institute, Oakland University, Rochester, MI 48309 USA.
Michelle L MilsteinEye Research Institute, Oakland University, Rochester, MI 48309 USA.
Amirali HosseinEunice Kennedy Shriver National Institutes of Child Health and Human Development, Intramural Research Program, National Institutes of Health, Bethesda, MD, 20892 USA.
Breyanna L CavanaughEye Research Institute, Oakland University, Rochester, MI 48309 USA.
Alexander J SodtEunice Kennedy Shriver National Institutes of Child Health and Human Development, Intramural Research Program, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0002-5570-8212
Andrew H BeavenEunice Kennedy Shriver National Institutes of Child Health and Human Development, Intramural Research Program, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0002-3006-3702
Andrew F X GoldbergEye Research Institute, Oakland University, Rochester, MI 48309 USA.ORCID 0000-0002-3964-5987

Funding

Molecular simulations of lipid curvature stress and its effect on transmembrane proteinsZIAHD008955 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SODT, ALEXANDER · 2016 to 2025
$6.2M
Molecular Basis of Rod and Cone Photoreceptor Outer Segment StructuresR01EY025291 · NEI · OAKLAND UNIVERSITY · PI GOLDBERG, ANDREW FX · 2016 to 2025
$3.5M
Intramural NIH HHS ZIA HD008955NEI NIH HHS R01 EY025291
6 · The paper itself

Abstract

Rod and cone photoreceptors are sensory neurons required for the first steps of image-forming vision. Mutations in

Indexed as

cell biologycomputational biologydisk rimgenetic diseasemembrane biogenesismembrane curvaturemolecular dynamicsouter segmentphotoreceptorprotein-protein interactionretinaretinal degenerationscaffold proteintetraspaninvision

Identifiers

PMID42146502
PMCPMC13174689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.