Evidence map›Paper›PMID 42146497›Full record

ArticlebioRxiv : the preprint server for biology2026

Kv2-VAP interactions enhance presynaptic ER and mitochondrial calcium influx and the mobilization of vesicles from the reserve pool.

Cameron D Paton, Michael B Hoppa

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cameron D PatonDepartment of Biological Sciences, Dartmouth College, NH..ORCID 0000-0002-8437-5111
Michael B HoppaDepartment of Biological Sciences, Dartmouth College, NH..ORCID 0000-0003-2340-0915

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MIERKE, DALE F · 2016 to 2025
$25.9M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Neuronal Cell Biology of Kv2.1-induced Endoplasmic Reticulum/Plasma Membrane Contact sitesR01NS112365 · NINDS · COLORADO STATE UNIVERSITY · PI HOPPA, MICHAEL BLAKE, TAMKUN, MICHAEL M. · 2020 to 2024
$2.0M
Super-resolution spinning disk confocal microscope for Dartmouth Life SciencesS10OD032310 · OD · DARTMOUTH COLLEGE · PI AHMED, YASMATH · 2022 to 2022
$600k
The Role of VAP Membrane Contact Sites in Axonal Calcium Dynamics and Synaptic TransmissionF31NS141318 · NINDS · DARTMOUTH COLLEGE · PI Cameron D Paton · 2025 to 2026
$100k
NCI NIH HHS P30 CA023108NIDDK NIH HHS P30 DK117469NIGMS NIH HHS P20 GM113132NIH HHS S10 OD032310NINDS NIH HHS F31 NS141318NINDS NIH HHS R01 NS112365
6 · The paper itself

Abstract

In neurons, the endoplasmic reticulum (ER) forms an extensive network that establishes membrane contact sites (MCSs) with various organelles including the plasma membrane (PM). While MCSs are known to regulate lipid exchange and Ca

Identifiers

PMID42146497
PMCPMC13174469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.