Evidence map›Paper›PMID 42146489›Full record

ArticlebioRxiv : the preprint server for biology2026

Met regulates endoderm migration in zebrafish.

Po-Shu Tu, Aaliyah M Ruiz-Corral, Stephanie Woo, Stefan C Materna

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Po-Shu TuQuantitative and Systems Biology Graduate Program, University of California Merced, Merced, California, 95343, USA.ORCID 0000-0003-0494-3658
Aaliyah M Ruiz-CorralQuantitative and Systems Biology Graduate Program, University of California Merced, Merced, California, 95343, USA.ORCID 0009-0001-7760-0018
Stephanie WooQuantitative and Systems Biology Graduate Program, University of California Merced, Merced, California, 95343, USA.ORCID 0000-0002-1238-8167
Stefan C MaternaQuantitative and Systems Biology Graduate Program, University of California Merced, Merced, California, 95343, USA.ORCID 0000-0003-1737-2479

Funding

Determining the role of cellular forces in endoderm differentiation and developmentR21HD107313 · NICHD · UNIVERSITY OF CALIFORNIA, MERCED · PI WOO, STEPHANIE · 2022 to 2023
$327k
NICHD NIH HHS R21 HD107313
6 · The paper itself

Abstract

Cells can employ different modes of migration, switching between them depending on context. However, how migration modes are determined remains incompletely understood. The mode of migration depends not only on external signals and guidance cues but also on which cell surface receptors a cell expresses. Receptor tyrosine kinases (RTKs) are central mediators of many processes including cell migration, yet whether RTK signaling mediates shifts in migratory behavior in vivo remains unclear. Here, we show that the RTK Met promotes persistent, directional migration of endodermal cells during gastrulation in zebrafish.

Identifiers

PMID42146489
PMCPMC13174448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.