Evidence map›Paper›PMID 42146488›Full record

ArticlebioRxiv : the preprint server for biology2026

Allosteric Biosensors Unravel GTPase-Effector Feedback.

Mingyu Choi, Roshan Ravishankar, Lihua He, Yu Yan, Danielle Lee, Gaudenz Danuser, Klaus Hahn

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingyu ChoiDepartment of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.
Roshan RavishankarLyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, USA.
Lihua HeDepartment of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.
Yu YanDepartment of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.
Danielle LeeDepartment of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.
Gaudenz DanuserLyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-8583-2014
Klaus HahnDepartment of Pharmacology, UNC Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-1970-7562

Funding

Dissecting signaling in vivo via precise control and visualization of protein activityR35GM122596 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Klaus M. Hahn · 2017 to 2026
$7.4M
NIGMS NIH HHS R35 GM122596
6 · The paper itself

Abstract

Fluorescent biosensors that report protein conformation

Identifiers

PMID42146488
PMCPMC13174374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.