Evidence map›Paper›PMID 42146456›Full record

ArticlebioRxiv : the preprint server for biology2026

India H Reiss, Jonathan D Cooper, Erik S Musiek, Robi David Mitra

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

India H ReissDepartment of Genetics, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-8785-0662
Jonathan D CooperDepartment of Genetics, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-1339-4750
Erik S MusiekDepartment of Neurology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-8873-0360
Robi David MitraDepartment of Genetics, Washington University in St. Louis, School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-2680-4264

Funding

Systematic and scalable phenotyping of mouse mutants for neuropsychiatric disease geneticsRM1MH138313 · NIMH · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Harrison W Gabel · 2025 to 2026
$4.9M
PARALLEL ANALYSIS OF TRANSCRIPTION AND PROTEIN-DNAINTERACTIONS IN SINGLE CNS CELLSRF1MH117070 · NIMH · WASHINGTON UNIVERSITY · PI DOUGHERTY, JOSEPH D, MITRA, ROBI D · 2018 to 2020
$3.2M
Deciphering epigenetically-regulated pathways to improve targeted therapy for invasion and metastasis in head and neck cancerR01DE032865 · NIDCR · WASHINGTON UNIVERSITY · PI Robi D Mitra, Sidharth Venkata Puram · 2023 to 2026
$2.4M
Deciphering the cis-regulatory logic of circadian reprogramming in a mouse model of Alzheimer's DiseaseF31AG076286 · NIA · WASHINGTON UNIVERSITY · PI REISS, INDIA H · 2022 to 2024
$101k
NIA NIH HHS F31 AG076286NIDCR NIH HHS R01 DE032865NIMH NIH HHS RF1 MH117070NIMH NIH HHS RM1 MH138313
6 · The paper itself

Abstract

Astrocytic homeostatic programs, many of which are regulated by the circadian clock, are disrupted early in neurodegenerative disease. The core clock transcription factor (TF) BMAL1 is required for normal astrocyte function, but its role during disease remains unclear. This is partly because methods for identifying cell type-specific TF binding sites are limited. Here, we developed MACS-Calling Cards (MACS-CC), a strategy for mapping astrocyte-specific TF occupancy

Identifiers

PMID42146456
PMCPMC13174507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.